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Showing 1 to 12 of 177 entries
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The Role of Pulmonary Artery Wedge Pressure on the Incidence of Atrial Fibrillation and Atrial Tachycardias in Patients With Isolated Pre-capillary Pulmonary Hypertension.

Physiological research

Dusik M, Fingrova Z, Ambroz D, Jansa P, Linhart A, Havranek S.
PMID: 34717065
Physiol Res. 2021 Dec 30;70(6):841-849. doi: 10.33549/physiolres.934706. Epub 2021 Oct 30.

Atrial fibrillation and atrial tachycardias (AF/AT) have been reported as a common condition in patients with pulmonary hypertension (PH). As yet, limited data exists about the significance of the borderline post-capillary pressure component on the occurrence of AF /...

Age-Related Progression of Microvascular Dysfunction in Cystic Fibrosis: New Detection Ways and Clinical Outcomes.

Physiological research

Kreslová M, Sýkorová A, Bittenglová R, Schwarz J, Pomahačová R, Jehlička P, Kobr J, Trefil L, Sýkora J.
PMID: 34717066
Physiol Res. 2021 Dec 30;70(6):893-903. doi: 10.33549/physiolres.934743. Epub 2021 Oct 30.

There are concerns about altered vascular functions that could play an important role in the pathogenesis and influence the severity of chronic disease, however, increased cardiovascular risk in paediatric cystic fibrosis (CF) has not been yet fully understood. Aim...

Age-Dependent Changes in the Function of Mitochondrial Membrane Permeability Transition Pore in Rat Liver Mitochondria.

Physiological research

Endlicher R, Drahota Z, Kučera O, Červinková Z.
PMID: 34717067
Physiol Res. 2021 Dec 30;70(6):905-911. doi: 10.33549/physiolres.934734. Epub 2021 Oct 30.

Mitochondria play an important role in the cell aging process. Changes in calcium homeostasis and/or increased reactive oxygen species (ROS) production lead to the opening of mitochondrial permeability transition pore (MPTP), depolarization of the inner mitochondrial membrane, and decrease...

Negative association between lipoprotein associated phospholipase A2 activity and baroreflex sensitivity in subjects with high normal blood pressure and a positive family history of hypertension.

Physiological research

Čelovská D, Vlčková K, Gonsorčík J.
PMID: 33676381
Physiol Res. 2021 Apr 30;70(2):183-191. doi: 10.33549/physiolres.934467. Epub 2021 Mar 08.

The relationship between baroreflex sensitivity (BRS) and inflammatory vascular biomarker Lipoprotein associated phospholipase A2 (Lp-PLA2) in subjects with high normal blood pressure (HNBP, prehypertensives) with a positive family history of hypertension (FHH+) and hypertension history free control subjects (FHH-)...

Phenotype and function of macrophage polarization in monocrotaline-induced pulmonary arterial hypertension rat model.

Physiological research

Fan Y, Hao Y, Gao D, Li G, Zhang Z.
PMID: 33676385
Physiol Res. 2021 Apr 30;70(2):213-226. doi: 10.33549/physiolres.934456. Epub 2021 Mar 08.

Pulmonary arterial hypertension (PAH) isa fatal disease characterized by vascular remodeling and chronic inflammation. Macrophages are the key orchestrators of inflammatory and repair responses, and have been demonstrated to be vital in the pathogenesis of PAH. However, specific phenotype...

An association between rs7635818 polymorphism located on chromosome 3p12.3 and the presence of abdominal aortic aneurysm.

Physiological research

Rašiová M, Habalová V, Židzik J, Koščo M, Farkašová Ľ, Moščovič M, Hudák M, Javorský M, Tkáč I.
PMID: 33676387
Physiol Res. 2021 Apr 30;70(2):193-201. doi: 10.33549/physiolres.934624. Epub 2021 Mar 08.

The association between gene variant rs7635818 located on chromosome 3p12.3 and abdominal aortic aneurysm (AAA) was not unambiguously determined by the results of genome-wide association studies. The aim of our study was to examine this possible association in the...

The Association Between Three Adipocytokines (Adiponectin, Resistin and Visfatin) And Thyroid Status in Patients With Type 2 Diabetes Mellitus and Autoimmune Thyroiditis.

Physiological research

Sotak Š, Schroner Z, Lazúrová I, Felšőci M, Jochmanová I, Petrášová D, Bertková I, Mitníková M, Nováková B, Wagnerová H, Bobelová O.
PMID: 34717061
Physiol Res. 2021 Dec 30;70(6):865-874. doi: 10.33549/physiolres.934701. Epub 2021 Oct 30.

Autoimmune thyroiditis (AIT) and type 2 diabetes mellitus (DM2) are the most common endocrinological diseases worldwide. Relation between these diseases explains several hypotheses. One of them is influence of some adipocytokines. This study evaluated association between three adipocytokines (adiponectin,...

Dynamic changes of high-sensitivity troponin T concentration during infancy: Clinical implications.

Physiological research

Jehlicka P, Rajdl D, Sladkova E, Sykorova A, Sykora J.
PMID: 33453718
Physiol Res. 2021 Mar 17;70(1):27-32. doi: 10.33549/physiolres.934453. Epub 2021 Jan 14.

Cardiac troponin T determination plays a dominant role in diagnosis of myocardial pathologies. Despite generally accepted use of high-sensitive cardiac troponin T assays (hscTnT) and clearly defined cut-off limit in adults, the uncertainty persists in infants. The aim of...

The effects of spaceflight microgravity on the musculoskeletal system of humans and animals, with an emphasis on exercise as a countermeasure: a systematic scoping review.

Physiological research

Moosavi D, Wolovsky D, Depompeis A, Uher D, Lennington D, Bodden R, Garber CE.
PMID: 33992043
Physiol Res. 2021 Apr 30;70(2):119-151. doi: 10.33549/physiolres.934550.

The purpose of this systematic review is twofold: 1) to identify, evaluate, and synthesize the heretofore disparate scientific literatures regarding the effects of direct exposure to microgravity on the musculoskeletal system, taking into account for the first time both...

Age-Dependent Changes in the Function of Mitochondrial Membrane Permeability Transition Pore in Rat Liver Mitochondria.

Physiological research

Endlicher R, Drahota Z, Kučera O, Červinková Z.
PMID: 34717067
Physiol Res. 2021 Oct 30;70(6). Epub 2021 Oct 30.

Mitochondria play an important role in the cell aging process. Changes in calcium homeostasis and/or increased reactive oxygen species (ROS) production lead to the opening of mitochondrial permeability transition pore (MPTP), depolarization of the inner mitochondrial membrane, and decrease...

Androgens in SARS-CoV-2 coronavirus infections.

Physiological research

Stárka L, Dušková M.
PMID: 34913348
Physiol Res. 2021 Dec 16;70:S145-S151.

Recent molecular biology findings have shown that for the penetration of the SARS-CoV-2 coronavirus into host cells, a key role is played by protease serine 2, the activity of which is dependent on androgens. The important role of androgens...

Could the CCR5-Delta32 mutation be protective in SARS-CoV-2 infection?.

Physiological research

Starcevic Cizmarevic N, Kapovic M, Roncevic D, Ristic S.
PMID: 34913355
Physiol Res. 2021 Dec 16;70:S249-S252.

Increasing evidence points to host genetics as a factor in COVID-19 prevalence and outcome. CCR5 is a receptor for proinflammatory chemokines that are involved in host responses, especially to viruses. The CCR5-delta32 minor allele is an interesting variant, given...

Showing 1 to 12 of 177 entries